We don't ask you to take absorption on faith. Each ingredient in an AlchemyPet formula is here, with the study behind it. Read the labels. Then read the science.
Helps reduce inflammation and support natural pain relief for improved joint comfort and mobility.
Mitidol® (Acmella + Ginger): Studied for pain management. In vitro studies show interaction with CB2 receptors and FAAH inhibition. A human trial on Mitidol® (50 subjects) showed support for knee comfort and function. Acmella itself is known for analgesic properties (spilanthol).
Read the studyFruiting Body Extract
ImmunityEnhances immune function, anti-inflammatory, and antioxidant effects.
Studied for its immunomodulatory effects, potentially stimulating the immune system due to beta-glucan content. Some research explores anti-tumor and anti-viral activities. More human clinical trials are needed for conclusive evidence.
Read the studySupports brain development, cognitive function, and vision.
alphamega³®/Algal DHA: DHA is essential for brain function and cognitive and visual development. It also supports heart health. alphamega³® is a plant-based, algal source of DHA, avoiding the fish supply chain and its contaminant load.
Read the studyAntioxidant-rich, supports cardiovascular and metabolic health.
Rich in Vitamin C and antioxidants. Studied for its benefits on cardiovascular health (lipid profiles, endothelial function), antioxidant effects, digestive health, and liver support. Crominex®3+ utilizes Amla (as Capros®) for its antioxidant properties to stabilize chromium.
Read the studyReduces stress and anxiety, supports adrenal function, and may improve sleep quality.
Clinically shown to have adaptogenic and anxiolytic effects, reducing stress and anxiety in healthy adults. Supports overall well-being.
Read the studyPowerful antioxidant, supports skin health, joint pain reduction, and enhances immune response.
Immune system booster, cardiovascular health support, and anti-aging properties.
Traditionally used as an adaptogen and for immune support. Studies suggest it may enhance immune response, protect against oxidative stress, and support cardiovascular health.
Read the studySupports eye health, circulation, and antioxidant defense.
Rich in anthocyanins. Studied for supporting vision health (eye fatigue, tear secretion, ocular circulation), antioxidant activity, and anti-inflammatory effects. Mirtoselect® is a standardized whole-fruit extract whose natural matrix delivers anthocyanins several times more bioavailably than purified anthocyanin fractions.
Read the studySupports joint comfort and helps calm inflammation for easier movement.
Boswellic acids are the active compounds in frankincense, long used for inflammatory conditions. Their weak point has always been absorption. Casperome® is a lecithin (Phytosome®) delivery form of standardized Boswellia serrata built to solve that, carrying the full bouquet of boswellic acids into circulation. In a controlled study it improved joint comfort, pain-free walking distance, and inflammatory markers.
Read the studySupports liver detoxification, antioxidant properties, and blood purification.
Shown to act on canine dermal fibroblasts (upregulation of SOD2). Traditionally used for detoxification, skin health, and as an anti-inflammatory. Human clinical evidence for specific conditions is still developing.
Read the studyHelps regulate blood sugar and support insulin sensitivity.
Crominex®3+: A complex of chromium, Amla, and Shilajit. Clinical studies on Crominex®3+ show it improves endothelial function, blood sugar, and lipid profiles, particularly when added to fish oil. Chromium itself aids insulin action and macronutrient metabolism.
Read the studyAnti-inflammatory properties, can help with joint health and mobility.
Turmacin®/Curcumin: General curcumin is reviewed for its anti-inflammatory and antioxidant effects. Turmacin® (a specific water-soluble turmeric extract, not just curcuminoids) has clinical studies supporting its efficacy for joint discomfort and mobility in healthy individuals and those with knee osteoarthritis.
Enhances nutrient absorption, supports detoxification, reduces inflammation.
A study on carbohydrate-derived fulvic acid (CHD-FA) assessed safety and proof-of-concept efficacy related to allergic responses. Fulvic acid is a key component of Shilajit, contributing to its antioxidant, anti-inflammatory, and cognitive-enhancing properties, and it helps carry minerals across the gut wall.
Read the studyHelps reduce inflammation and support natural pain relief for improved joint comfort and mobility.
Mitidol® (Ginger + Acmella): Studied for pain management (see Acmella). Ginger itself is well-known for anti-inflammatory, anti-nausea, and digestive support properties due to gingerols and shogaols.
Read the studySupports cognitive function, memory, and circulation.
Virtiva® (Ginkgo + Phosphatidylserine): This combination is clinically studied to support cognitive functions like memory (working memory, consolidation, speed), attention, and choice reaction time. Ginkgo Biloba alone is studied for improving circulation and cognitive function.
Read the studyPowerful antioxidant, supports cardiovascular health and reduces inflammation.
Cardiovascular health benefits, strong antioxidant properties, supports anti-inflammatory processes.
Olea25®/Hydroxytyrosol: A very potent antioxidant found in olives. Supports cardiovascular health and has anti-inflammatory properties. Olea25® is promoted for its high ORAC value and cellular protection.
Read the studyFruiting Body Extract
CognitionSupports cognitive health, nerve regeneration and immune system.
Studied for its neuroprotective properties, supporting cognitive function (memory, concentration) by potentially stimulating Nerve Growth Factor (NGF).
Read the studySupport eye health, reduce oxidative stress, and enhance immune response.
XanthoSight® (Lutein, Zeaxanthin, Meso-Zeaxanthin): Clinically studied to increase macular pigment optical density, improve visual performance (contrast, acuity, glare recovery), and filter harmful blue light, supporting overall eye health and potentially cognitive function.
Read the studyRegulates sleep cycles, supports antioxidant defenses, and has a calming effect studied directly in dogs.
The body's own sleep hormone, synthesized from tryptophan in the pineal gland and released on a light-driven daily rhythm. Beyond sleep, melatonin acts as a broad-spectrum antioxidant and signaling molecule across mammalian systems, from circadian timing to gut and immune function. In dogs it is studied as a mild calming aid and a sleep support for senior animals.
Boosts energy levels, enhances mental performance and immune function.
An adaptogen studied for improving stamina, concentration, reducing fatigue, supporting immune function, and potentially benefiting mood and cognitive performance.
Read the studySupports anxiety and insomnia, potentially beneficial for nervous system health.
Traditionally used for anxiety and insomnia. Clinical studies suggest it may be effective in reducing anxiety and improving sleep quality, possibly by increasing GABA levels in the brain.
Read the studySupports brain cell function and cognitive performance.
Virtiva® (Ginkgo + Phosphatidylserine): This combination supports cognitive functions (see Ginkgo). Phosphatidylserine itself is a key component of cell membranes and is crucial for cognitive function, memory, attention, and stress reduction (by modulating cortisol).
Read the studyAdaptogenic properties, helps with stress management, and enhances physical and mental stamina.
An adaptogen studied for its ability to reduce fatigue, improve mental and physical performance under stress, support mood, and enhance endurance.
Read the studyEnhances nutrient absorption, supports energy production and recovery.
PrimaVie®/Shilajit: A natural phytocomplex rich in fulvic acid with procognitive potential. PrimaVie® is clinically studied to boost testosterone, improve sperm quality, enhance muscle strength and recovery, preserve bone density, and support collagen synthesis. Its fulvic acid also improves the bioavailability of the minerals it carries.
Supports digestive health, detoxification, and antioxidant function.
A cornerstone fruit in Ayurvedic medicine, rich in tannins, chebulagic acid, and polyphenols. Studied for digestive support, antioxidant activity, and gut health. Standardized forms such as AyuFlex® have been researched across multiple human trials for joint comfort, mobility, and endothelial function.
Read the studyFruiting Body Extract
ImmunitySupports immune health, rich in polysaccharides and antioxidants.
A functional mushroom rich in polysaccharopeptides (PSK and PSP) and beta-glucans. Studied for immunomodulatory effects, antioxidant activity, and supporting a balanced immune response. Frequently researched as an adjunct in immune health.
Read the studySupports immune health by providing natural antioxidants that defend cells and maintain a balanced immune response.
Vitamin C (ascorbic acid) is a water-soluble antioxidant that helps protect cells from oxidative stress and supports normal immune function, collagen synthesis, and iron absorption. Dogs synthesize some Vitamin C on their own, but supplemental intake can support immune resilience during periods of stress, aging, or heightened demand.
Read the studyDirects calcium to bone and away from arteries, supporting skeletal and cardiovascular health.
Vitamin K2 activates the proteins that route calcium where it belongs. It helps carboxylate osteocalcin, which binds calcium into bone, and matrix Gla protein (MGP), which keeps calcium out of arterial walls and soft tissue. This dual role links K2 to both bone density and cardiovascular health, and it works alongside Vitamin D in calcium metabolism.
Read the studyAids in fat metabolism, supports energy production, and may improve exercise performance.
Carniking®/L-Carnitine: Studied directly in dogs. In Labrador Retrievers, Carniking® improved lean mass, exercise recovery, and antioxidant capacity, and helped prevent weight gain on high-calorie diets. Mechanistically, L-carnitine transports fatty acids into the mitochondria for energy, sparing muscle and supporting metabolic health.
Promotes relaxation without drowsiness, may improve focus and mental clarity.
An amino acid found in tea. Clinically studied to promote relaxation without drowsiness, reduce stress, improve focus and attention (especially with caffeine), and support sleep quality by increasing alpha brain waves.
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Where we could, we chose branded, clinically studied ingredients over commodity botanicals. That means the research below was funded and published by the ingredient makers, and a veterinarian can read the upstream trials directly rather than take our word for it.
Several of these trials were run in dogs. The rest are human studies on the specific branded material. These describe the ingredients as supplied to us, not finished AlchemyPet formulas. Our own contribution is the second layer of delivery: alginate microencapsulation that protects these actives on the way to where absorption happens.
Dogs on Crominex®3+ showed a significant reduction in arthritic pain, measurable by day 90 and greatest at day 150, across overall pain, pain on limb manipulation, and pain after exertion. Placebo pain held steady or rose. Kidney, liver, and muscle serum markers stayed normal, indicating it was well tolerated.
Labradors on Carniking® with exercise gained lean mass while the control group lost it, and showed lower creatine kinase and myoglobin (markers of muscle damage) plus improved antioxidant capacity. The researchers noted the results are especially promising for senior pets, where preserving muscle is an unmet need.
In older Labradors fed high-calorie diets, Carniking® prevented weight gain, reduced feed intake, and raised basal metabolic rate, effects that held independent of exercise and were strongest in females. Plasma L-carnitine rose dose-dependently, tying the outcomes to the supplement.
Natreon's three joint actives each showed reductions in a distinct pain measure in moderately arthritic dogs: PrimaVie® on pain during limb manipulation, AyuFlex® on overall pain, and Crominex®3+ on pain after physical exertion. Together they cover the range of ways arthritis pain shows up day to day.
Added to standard care, this lecithin delivery form of Boswellia raised pain-free walking distance from about 35 m to 188 m, cut local pain and joint effusion, and lowered the cartilage-damage marker COMP and inflammatory CRP. It is a clean example of a delivery innovation making a poorly-absorbed active work harder.
Across a clinical program of six trials, AyuFlex® significantly improved joint comfort and mobility (WOMAC, KOOS, VAS) in people with knee discomfort, and improved endothelial function and oxidative-stress markers in metabolic syndrome and type 2 diabetes. The lower 250 mg dose performed on par with 500 mg.
Complexing Ginkgo with phosphatidylserine (the Virtiva® form) improved secondary memory and sped up memory-task performance where plain Ginkgo at the same dose did not, and all treatments improved calmness. A separate study in elite athletes found Virtiva® lowered stress-induced cortisol.
Mirtoselect® significantly improved tear secretion and antioxidant potential in people with dry-eye symptoms, most in those with the driest eyes. Its whole-fruit matrix delivered anthocyanins about four times more bioavailably than a purified anthocyanin fraction, evidence that the natural matrix, not just the marker compound, drives the effect.
The three macular carotenoids in XanthoSight® filter high-energy blue light and are clinically shown to raise macular pigment optical density in as little as six months, improving glare recovery, contrast sensitivity, and visual processing speed. Meso-zeaxanthin, the most potent of the three, is hard to obtain from diet alone.
Standardized to at least 50% fulvic acid, PrimaVie® is backed by eight clinical studies showing gains in ATP and endurance, upregulation of collagen-synthesis genes, and a lower inflammatory marker (hsCRP). The fulvic acid also enhances the bioavailability of the trace minerals it carries, an absorption story in its own right.